TB-500

Also known as Thymosin Beta-4 fragment, TB4

Synthetic fragment related to Thymosin Beta-4 studied for tissue repair.

Category
healing
Route
subq
Documented dose
2000–5000 mcg
Typical frequency
Twice weekly loading, then weekly
Cycle
6 weeks on, 4 off
Half-life
~2-3 days (estimated)
Common vial sizes
2 mg, 5 mg, 10 mg
Regulatory status
Not approved for human use; banned by WADA.

What it does

A synthetic version of an active piece of Thymosin Beta-4, a protein involved in cell movement and repair. It helps cells migrate into damaged areas and encourages new blood vessels to grow there. What people look into it for: • Muscle, tendon and ligament recovery after injury or hard training • Better flexibility and less scar-tissue stiffness • Wound healing and reduced inflammation • Heart tissue repair in animal research It is often paired with BPC-157: TB-500 works more systemically throughout the body while BPC-157 works strongly at the site of injury.

Mechanism

Binds G-actin and promotes actin polymerisation, cell migration and angiogenesis.

Storage — lyophilised

Refrigerate 2-8C, protect from light.

Storage — reconstituted

Refrigerate 2-8C, use within ~28 days.

Reconstitution notes

Add 2 ml bacteriostatic water to a 5 mg vial for 25 mcg per unit.

Commonly stacked with

  • BPC-157

Commonly reported side effects

  • Fatigue after dosing
  • Head rush
  • Injection-site irritation

Contraindications noted

  • Active malignancy (theoretical)
  • Pregnancy or breastfeeding

Research notes

Human data limited; most claims extrapolated from animal wound-healing models.

Track this properly

Work out syringe units with the free calculator, or set up a full schedule in about a minute.

Reference information only, not medical advice. See our medical disclaimer.