GHK-Cu
Also known as Copper peptide, Glycyl-L-histidyl-L-lysine copper
Copper-binding tripeptide used topically and subcutaneously for skin and hair.
- Category
- skin
- Route
- subq
- Documented dose
- 1000–2000 mcg
- Typical frequency
- Once daily or topical
- Cycle
- 4 weeks on, 4 off
- Half-life
- ~1 hour
- Common vial sizes
- 50 mg, 100 mg
- Regulatory status
- Cosmetic ingredient; injectable use not approved.
What it does
A copper-carrying peptide that occurs naturally in the body and drops sharply as we age. It signals skin and connective tissue to rebuild, and is one of the most widely used peptides in cosmetics. What people look into it for: • Firmer skin, fewer fine lines and better elasticity through more collagen • Faster wound healing and less visible scarring • Hair thickness and follicle support • Calming inflammation and mopping up free radicals It is used both topically (creams and serums) and by injection, with topical use being by far the most common.
Mechanism
Copper carrier peptide modulating collagen, elastin and antioxidant gene expression.
Storage — lyophilised
Refrigerate 2-8C, protect from light.
Storage — reconstituted
Refrigerate 2-8C, use within ~28 days.
Reconstitution notes
Add 5 ml bacteriostatic water to a 50 mg vial; injections commonly sting.
Commonly stacked with
- BPC-157
Commonly reported side effects
- Injection-site stinging
- Blue discolouration at site
- Copper accumulation with overuse
Contraindications noted
- Wilson disease
- Pregnancy or breastfeeding
Research notes
Topical use is far better supported than injectable use.
Track this properly
Work out syringe units with the free calculator, or set up a full schedule in about a minute.
Reference information only, not medical advice. See our medical disclaimer.