BPC-157

Also known as Body Protection Compound 157, PL 14736

Gastric pentadecapeptide studied for soft-tissue and gut repair.

Category
healing
Route
subq
Documented dose
200–500 mcg
Typical frequency
Once or twice daily
Cycle
6 weeks on, 4 off
Half-life
~4 hours (subcutaneous, estimated)
Common vial sizes
5 mg, 10 mg
Regulatory status
Not approved for human use; research chemical in most jurisdictions.

What it does

A stable copy of a protective peptide found naturally in stomach fluid. Its main reputation is speeding up repair in tissue that normally heals slowly, and calming inflammation where it is applied or injected. What people look into it for: • Tendon, ligament and muscle injuries that are slow to heal • Gut problems such as ulcers, leaky gut, IBD-type inflammation and NSAID damage • Joint pain and post-surgical or post-injury recovery • Better blood-vessel growth into healing tissue, which brings in oxygen and nutrients • Some reports of improved mood and nerve recovery The animal evidence is broad and consistent; controlled human trials are still limited.

Mechanism

Appears to upregulate VEGF-driven angiogenesis and growth-factor receptor expression at injury sites; modulates the nitric-oxide system.

Storage — lyophilised

Refrigerate 2-8C; stable at room temperature short term, protect from light.

Storage — reconstituted

Refrigerate 2-8C, use within ~28 days.

Reconstitution notes

Add 2 ml bacteriostatic water to a 5 mg vial for 25 mcg per insulin-syringe unit.

Commonly stacked with

  • TB-500
  • KPV

Commonly reported side effects

  • Injection-site irritation
  • Lightheadedness
  • Nausea

Contraindications noted

  • Active malignancy (theoretical, via angiogenesis)
  • Pregnancy or breastfeeding

Research notes

Almost all evidence is preclinical rodent data; no large human trials published.

Track this properly

Work out syringe units with the free calculator, or set up a full schedule in about a minute.

Reference information only, not medical advice. See our medical disclaimer.