5-Amino-1MQ
Also known as 5-Amino-1-methylquinolinium
Small molecule NNMT inhibitor used in metabolic stacks.
- Category
- fat loss
- Route
- oral
- Documented dose
- 50000–150000 mcg
- Typical frequency
- Once daily
- Cycle
- 8 weeks on, 4 off
- Half-life
- Unclear
- Common vial sizes
- 50 mg, 100 mg
- Regulatory status
- Not approved; sold as a research compound.
What it does
A small molecule taken by mouth that is being looked at for fat loss and cellular energy. It blocks an enzyme (NNMT) that fat cells use to stay large and sluggish, which frees up more NAD+ — the fuel cells use to make energy. What people look into it for: • Losing body fat, especially stubborn fat, without losing muscle • More day-to-day energy and better exercise tolerance • Better blood-sugar handling and metabolic health • Supporting healthy ageing through higher NAD+ levels Most of the evidence so far comes from animal and lab studies rather than large human trials.
Mechanism
Inhibits nicotinamide N-methyltransferase, raising intracellular NAD+ in adipocytes.
Storage — lyophilised
Store cool and dry.
Storage — reconstituted
Refrigerate if reconstituted; use within ~28 days.
Reconstitution notes
Most commonly taken as oral capsules rather than injection.
Commonly stacked with
- MOTS-c
- NAD+
Commonly reported side effects
- Insomnia
- Jitteriness
- Nausea
Contraindications noted
- Pregnancy or breastfeeding
Research notes
Only mouse data available for the fat-loss claims.
Track this properly
Work out syringe units with the free calculator, or set up a full schedule in about a minute.
Reference information only, not medical advice. See our medical disclaimer.